TUF Love for “Junk” DNA

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TUF Love for “Junk” DNA

The widespread occurrence of noncoding (nc) RNAs--unannotated eukaryotic transcripts with reduced protein coding potential--suggests that they are functionally important. Study of ncRNAs is increasing our understanding of the organization and regulation of genomes.

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The Case for Junk DNA

With the advent of deep sequencing technologies and the ability to analyze whole genome sequences and transcriptomes, there has been a growing interest in exploring putative functions of the very large fraction of the genome that is commonly referred to as ‘‘junk DNA.’’ Whereas this is an issue of considerable importance in genome biology, there is an unfortunate tendency for researchers and sc...

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Junk DNA - repetitive sequences

Eukaryote and also human DNA contains large portion of noncoding sequences. As for the coding DNA, the noncoding DNA may be unique or in more identical or similar copies. DNA sequences with high copy numbers are then called repetitive sequences. If the copies of a sequence motif lie adjacent to each other in a block, or an array, we are speaking about tandem repeats, the repetitive sequences di...

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The role of Junk DNA

Many efforts have been done in order to explain the role of junk DNA, but its function remain to be elucidated. In addition the GC-content variations among species still represent an enigma. Both these two mysteries can have a common explanation: we hypothesize that the role of junk DNA is to preserve the mutations probability that is intrinsically reduced in GC-poorest genomes.

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Competing chromosomes explain junk DNA.

sciencemag.org SCIENCE Paleoindian, and fishtail points previously provided a roadmap that archaeologists used to trace the spread of Paleoindians throughout the Americas. Such a roadmap is lacking for pre-Clovis sites. Assemblages with distinctive stemmed (“tanged”) chipped-stone projectile points, crescents (lunate-shaped), and leaf-shaped bifaces found in Japan, northeast Asia, western North...

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ژورنال

عنوان ژورنال: Cell

سال: 2006

ISSN: 0092-8674

DOI: 10.1016/j.cell.2006.06.009